Knox College has had several principals throughout its history at 59 St. George Street, and at its previous homes. These are the many people who have led the College throughout its history.

Principal Micheal Willis 1857-1870

Principal William Caven 1873-1904

Principal William McLaren 1904-1909

Principal Alfred Gandier, 1909-1925

Principal Thomas Eakin, 1926-1940

Principal Walter W. Bryden, 1945-1952

Principal Stanley Glen, 1952-1976

Rev.Prof Allan Farris, Principal 1976-1977

Principal J.Charles Hay, 1978-1985

Principal Don Corbett, 1985-1990

Principal Art Van Seters, 1992-1999

Principal J.Dorcas Gordon, 1999-present